1. Εισαγωγή
Supplements have become a key part of modern health and wellness industries, spanning dietary supplement, collagen supplements, protein whey supplements and more. Σε αυτό το άρθρο, we will guide you through the most profitable supplement categories, popular supplement forms like tablets and capsules, leading supplement manufacturers, and essential machines such as semi automatic capsule filler, fully automatic encapsulation machine and tablet press equipment.

2. What Are the Best-Selling Supplements in the Market?
According to Grand View Research, the global dietary supplements market was valued at USD 177.5 billion in 2023 and is projected to reach USD 327.42 billion by 2030, growing at a CAGR of 9.1% from 2024 to 2030. This growth derives from the increasing consumer awareness of health, aging populations, and the demand for immunity-boosting and lifestyle-enhancing products.

From health improvement to beauty and performance, here below are the most in-demand supplements types and categories.
1) Καλύτερος-Selling Supplement Types Globally (Revenue Share 2024):
Supplement Category |
Global Market Share (%) |
Manufacturing Machinery Used |
Vitamins (e.g., D, B12, C) |
30.4% |
Capsule Filler, Tablet Press, Gummy Making Machine. |
Proteins & Amino Acids |
22.1% |
Capsule Filler Machine, Pill Press Machine. |
Omega-3/Fish Oil |
10.7% |
Softgel Encapsulation Machine. |
Probiotics |
9.3% |
Capsule Fillers, Stick Pack Machine. |
Herbal & Botanical Supplements |
8.6% |
Μηχανή πλήρωσης κάψουλας, Pill Pressing Machine. |
Minerals (e.g., Magnesium) |
6.9% |
Encapsulation Machine, Μηχάνημα πατώματος δισκίου |
2) Καλύτερος-Selling Supplements in Different Industries
For General Health Improvement:
- Magnesium Supplementμικρό:Supports muscle and nerve function and helps with energy production. Magnesium glycinate is popular for its high absorption and gentle effect on the stomach. It’s often chosen as the best magnesium supplement for overall wellness.
- Vitamin D Supplements:Essential for immune support and bone health. Vitamin D3 supplements are the most effective form to maintain adequate levels, especially in low sunlight areas. Many consider it the best vitamin D supplement for daily use.
- Calcium Supplements:Essential for strong bones and muscle function. Calcium citrate, often paired with vitamin D, improves absorption and bone strength. These supplements help decrease the risk of osteoporosis.
- Probiotic and Gut Health Supplements: Support a healthy gut microbiome and improve digestion. They also enhance immune function and reduce digestive discomfort. Many users seek the best gut health supplement for daily balance.

For Beauty and Skin Care:
- Collagen Supplements: Collagen helps remainskin elasticity and hydration. It’s popular for reducing signs of aging and improving skin texture. Collagen supplements are often used to combat sagging skin.
- Hair Growth Supplements:Including biotin, nourish hair follicles and reduce hair loss. They support stronger, thicker hair, especially for women. These supplements are favored for hair growth and health.

For Fitness & Muscle Building:
- Protein & Whey Supplements: Support muscle repair and growth after exercise. Whey protein is a fast-absorbing option popular among athletes. Many choose protein supplements to boost muscle mass.
- Pre-Workout & Fat Burner Supplements: Increase energy and focus during training. Fat burners help enhance metabolism and support natural weight loss. Both are popular for improving workout performance and body composition.
- Muscle Building Supplements: Such as creatine and BCAAs aid muscle growth and strength. They support intense training and recovery. These are commonly used by those aiming to gain muscle.

For Cognitive and Emotional Well-being
- Brain & Memory Supplements: These supplements boost focus, memory, and mental clarity. Ingredients like omega-3s and nootropics are commonly used. They help reduce brain fog and improve cognitive function.
- Natural Supplements for Anxiety: Natural supplements like ashwagandhaand vitamin B12 supplements, support calmness and reduce anxiety. They offer gentle mood support without prescription drugs. These are favored for emotional well-being.

3. Most Popular Supplement Format (2025):
The global supplement industry has evolved not only in the types of nutrients it delivers, but also in the formats used to deliver them. In 2025, consumer preference is heavily influenced by convenience, absorption efficiency, and user experience.
Here are the most popular supplement forms and the market share details (Estimated, 2025):
Form | Market Share (%) | Description | Manufacturing Machines |
Κάψουλες (Gelatin & Veggie) | 38% | – Easy to swallow and ideal for oil- or powder-based ingredients. – Common in probiotics, fish oil, and herbal supplements. | – Μηχανή πλήρωσης κάψουλας – Semi Automatic Capsule Filler – Fully Automatic Encapsulation Machine |
Δισκίο | 25% | – Compact, cost-effective, and have a long shelf life. – Often used for multivitamins and minerals. | – Tablet Pressing Machine – Rotary Tablet Press – Single Punch Table Press |
Powders | 15% | – Great for mixing with water or shakes. – Popular for protein, collagen, and greens supplements. | – Powder Mixing Machine – Powder Filling Machine – Sachet Packaging Machines |
Gummies | 12% | – Chewable and tasty, making them popular for children and adults. – Common for vitamins and beauty supplements. | – Gummy Making Machine – Gummy Packaging Machine |
Αναβραστικά δισκία | 4% | – Dissolvable in water and easy on the stomach. – Popular for vitamin C, electrolytes, and energy blends. | – Περιστροφική μηχανή πρέσας ταμπλετών – Tube Filling Machine |
Chewables | 3% | – Similar to gummies but firmer. – Great for calcium and kids’ supplements. | – Μηχάνημα πατώματος δισκίου – Tablet Coating Machine |
Σοφές | 2% | – Gelatin-based, smooth, and easy to digest. – Often used for omega-3, vitamin E, and other oil-based nutrients. | – Softgel Encapsulation Machine |
Liquids | 1% | – Fast absorption and ideal for people who struggle with pills. – Used for vitamins, herbal extracts, and elderberry syrup. | – Liquid Mixing Tanks – Liquid Filling Machines |
In 2025, capsules have emerged as the most popular supplement format across global markets. Their dominance is driven by excellent digestibility, consumer-friendly design, and formulation flexibility. Capsules are also favored for their clean-label appeal, ease of swallowing, and ability to mask unpleasant tastes or odors, making them a top choice for health-conscious consumers and brands alike.
4. Capsule vs Tablet vs Softgel vs Gummy: Which Supplement Form is Better?
With so many supplement formats available such as capsules, δισκίο, softgels, and gummies, it can be hard to choose the right one for your product or personal use. Each form has its own advantages and drawbacks depending on the ingredients, target users, and intended health benefits.

Here’s a side-by-side comparison to help you decide which format is best for your needs.
Form | Pros | Cons |
Κάψουλες | – Break down quickly in the stomach for faster absorption. – Can carry both powder and oil-based ingredients. – Often contain fewer binders and additives. – Available in gelatin or vegetarian forms. | – Sensitive to humidity and can become brittle or sticky. – Higher production cost compared to tablets. |
Δισκίο | – Most cost-effective and easy to mass-produce. – Compact, can hold higher active ingredient concentration. – Long shelf life and stable for storage and transport. | – May contain binders, coatings, and fillers that affect purity. – Slower to dissolve and harder to swallow. |
Σοφές | – Perfect for fat-soluble vitamins and oils (e.g., omega-3, vitamin E). – Sealed format protects ingredients from oxidation. – Smooth, easy to swallow. | – Typically made with gelatin (not suitable for vegetarians). – More costly and complex to manufacture. |
Gummies | – Great taste and chewabl, high compliance among children and adults. – No need for water or swallowing pills. Appealing for casual supplement users. | – Usually lower in active ingredient dosage. – Often contain sugars, artificial flavors, or gelatin. – Can melt or stick together in warm conditions. |
5. Top Global Supplement Manufacturers (B2B Focus)
The global supplement market is driven by a few key players who specialize in contract manufacturing, private labeling, and bulk supply for brands worldwide. Below are some of the most trusted and influential B2B supplement manufacturers in 2025:
Company | Headquarters | Specialties | Key Strengths |
Lonza | Switzerland | Κάψουλες, probiotics, custom formulations | Maker of Capsugel®; strong in vegetarian capsule innovation and pharma-grade supplements. |
DSM Nutritional Products | Netherlands | Vitamins, omega-3, immune support | Focused on science-backed ingredients and sustainability in B2B supply. |
Glanbia Nutritionals | Ireland / USA | Sports nutrition, functional foods, premix blends | Offers turnkey solutions and custom formulation services; strong in protein and wellness sectors. |
NBTY (The Nature’s Bounty Co.) | USA | Vitamins, beauty supplements, herbal blends | Offers large-scale OEM/ODM services with global distribution capability. |
Aker BioMarine | Norway | Krill oil, marine-based omega-3 | B2B supplier with sustainability certifications; highly regarded for brain and heart health ingredients. |
Iovate Health Sciences (Muscletech, Six Star) | Καναδάς | Sports nutrition, performance supplements | Known for cutting-edge formulations and high-volume private label production. |
Prinova | USA | Nutrient premixes, flavors, amino acids | Supplies ingredients and custom blends to major global supplement brands. |
These manufacturers offer end-to-end solutions from raw ingredient sourcing and R&D to encapsulation, bottling, labeling, and regulatory support, making them reliable partners for businesses scaling in the health and wellness sector.
6. How to Make Supplements with Equipment: Capsule Fillers & Tablet Presses Guide
After exploring the common supplement types and popular forms, understanding the production process and the key supplement manufacturing equipment involved is essential for manufacturers. Whether producing capsules or tablets, the choice of encapsulation machines and tablet pressing machines directly affects product quality, consistency, and manufacturing efficiency. Below are some featured machines from RUIDA PACKING, trusted for their reliability and advanced technology in supplement manufacturing machinery.
1) Semi-Automatic Capsule Filler CGNT209
This semi automatic capsule filling machine offers a cost-effective solution for small to medium production volumes. It supports powder filling into both gelatin and vegetarian capsules with high accuracy that reaches 97%. Its compact design allows easy operation and cleaning, making it ideal for startups or laboratories.

Βασικά Χαρακτηριστικά:
- Specially Treated Capsule Trays: Oxidized for enhanced hardness and a smooth surface, improving capsule feeding success rates.
- Precision-Machined Mold Chamfering: Accurate capsule placement, preventing missing capsules during the process.
- Horizontal Capsule Locking Station: Utilizes a pneumatic activation mechanism for secure locking, reducing labor intensity, minimizing powder leakage, and improving material utilization and product quality.
2)Fully Automatic Capsule Filling Machine NJP-1500D
Designed for large-scale production, this fully automated encapsulating machine features multi-lane capsule filling with high speed and precision. It handles powder, κόκκους, and liquid filling, with automatic capsule separation, locking, and ejection functions. The system improves efficiency while maintaining strict hygiene standards.

Βασικά Χαρακτηριστικά:
- High-Precision Cam Indexing Box: Completely resolved the frequent failures of the previous 83DS model, including input and output shaft breakages. 100DS indexing box, ensuring reliable continuous operation of the equipment.
- National Patent for Filling Mechanism: Three-dimensional adjustment for even force distribution on the measuring plate, allowing for precise and quick dosing.
- CNC-Machined Internal Groove Cam:Internal groove cam made in single operation from a CNC machining center, ensuring no seams or gaps for better stability, quiet operation during high-speed production.
3)Automatic Tablet Press Machine HGZP-40
This rotary tablet press is engineered for high-output tablet manufacturing with consistent size and weight. It supports various tablet shapes and thicknesses and includes advanced control systems to adjust pressure and speed for optimal hardness and production rates. Suitable for vitamins, minerals, and herbal supplements.

Βασικά Χαρακτηριστικά:
- Automatic Tablet Weight Adjustment System: Servo motor control of the filling track, no handwheel needed. The system can automatically adjust the filling amount according to the set value, with average tablet weight accuracy of ±2%.
- Real-time Online Detection & Rejection System: Automatically detects and rejects tablets that do not meet weight standards, supporting both continuous and single-piece rejection.
- Pre-compression System: Effectively removes air from the middle dies and powder, enhancing powder plasticity for the main compression and extending compression time, thus improving tablet quality.
7. Strategic Insights for Supplement Manufacturers and Sellers
With growing demand across health, beauty, and performance segments, supplement manufacturers and sellers must strategically align their operations to capitalize on market trends, focus on high-demand categories, prioritize producing and marketing supplements like collagen, magnesium, gut health probiotics, and women’s weight loss formulas to capture key consumer interests.
- Choose Consumer-Preferred Formats: Capsules remain the top choice for ease of digestion and flexible formulation, supporting better customer satisfaction and product differentiation.
- Partner with Trusted Manufacturers and Suppliers:Whether outsourcing or in-house, ensure partnerships that guarantee quality, regulatory compliance, and scalable production capacity.
- Invest in Efficient Production Equipment:Utilize reliable capsule fillers and tablet presses that meet your production scale, enabling consistent quality and streamlined operations.
8. Σύναψη
The global supplement market is rapidly evolving, driven by increasing consumer focus on health, beauty, and fitness. To stay competitive, businesses must prioritize trending supplement categories, select the right product formats and investing in advanced production equipment like capsule fillers and tablet presses ensures consistent quality and scalable output. With strategic alignment across product development, manufacturing, and marketing, supplement companies can effectively meet market demand and fuel long-term growth.